7092

• UCREFRP Catalog Number: 7092
• Author: Eisler, R.
• Title: Arsenic Hazards to Fish, Wildlife, and Invertebrates
• USFW Year: 1988.
• USFW - Doc Type: A Synoptic Review.
• Copyright Material: NO

Table 6. (continued)
Organism and arsenical Effect Referencea
Total inorganic arsenic Daily dose of 3 mg for 2 weeks
may cause severe poisoning in
infants, and symptoms of toxicity
in adults. 6
Cynmolgus monkey, Macaca sp.
Fish arsenic meal (witch
flounder, Glyptocephalus
cynoglossus) containing
77 mg total As/kg
As above, except arsenic
trioxide substituted
for total As
Mammals, many species
Calcium arsenate
Lead arsenate
Mammals, most species
Arsenic trioxide
Sodium arsenite
Mouse, Mus spp.
Arsenate
Arsenic trioxide
Arsenic trioxide
Given single meal at 1
mg/kg BW; tissue residues
normal after 14 days.
As above.
Single oral LD-50 range
of 35 to 100 mg/kg
BW.
Single oral LD-50 range
of 10 to 50 mg/kg
BW.
3 to 250 mg/kg BW
lethal.
1 to 25 mg/kg BW
lethal.
MatTgnal dose of 10 mg
As /kg BW results in some
fetal deaths and malfor-
mations.
Single oral LD-50 (96 hours)
value of 39.4 mg/kg BW; LD-0
(96 hours) of 10.4 mg/kg BW.
"Adapted" group (50 mg As/1
in drinking water for 3 months)
had subcutaneous LD-50 value
of 14 mg/kg BW vs. 11 for
non-adapted group.
66
11
11
3
3
12
12
3
12
12
J