7092

• UCREFRP Catalog Number: 7092
• Author: Eisler, R.
• Title: Arsenic Hazards to Fish, Wildlife, and Invertebrates
• USFW Year: 1988.
• USFW - Doc Type: A Synoptic Review.
• Copyright Material: NO

Table 6. (continued)
Organism and arsenical
Effect
Referencea
Horse, Equus caballus
Sodium arsenite Daily doses of 2 to 6 mg/kg
BW (1 to 3 grams) for 14
weeks is fatal.
Cat, Felis domesticus
Inorganic arsenate or Chronic oral toxicity at
arsenite 1.5 mg/kg BW.
Human, Homo sapiens
Arsenic trioxide Fatal at 70 to 180 mg,
equivalent to about 1
to 2.6 mg As/kg BW.
Arsenic trioxide LD-50 dose of 7 mg/kg
BW.
Cacodylic acid LD-50 of 1,350 mg/kg
BW.
Lead arsenate Some deaths at 7 mg/kg
BW.
Total arsenic Accumulations of 1 mg/kg
BW daily for 3 months in
children, or 80 mg/kg
BW daily for 3 years
produced symptoms of
chronic arsenic poisoning.
Total arsenic, daily oral Prolonged dosages of 3 to 4
dose mg daily produced clinical
symptoms of chronic arsenic
intoxication.
Total arsenic in drinking Prolonged use produced symptoms
and cooking water of chronic arsenic intoxica-
tion (0.6 mg/1) or skin cancer
(0.29 mg/1).
Total arsenic, probably 12,000 Japanese infants poisoned
as arsenate (128 deaths) from consumption
of dry milk contaminated with
arsenic; average exposure of
3.5 mg As daily for one month.
Severe hearing loss, brain wave
abnormalities, and other central
nervous system disturbances noted
15 years postexposure.
3
6
6
3
3
3
3
3
3
6
65