1992-04-02_REVISION - M1988112 - Laserfiche WebLink

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~i ,~s~ • • ___30 BIOLOGICAL REPORT 85(1.23) ' Table 4. Continued. Species, dose, end other variables Effects References ' Rock dove, Columba liuia 0.12 mg CN/L air, as HCN All dead in 10 min 2 1.6 mg CN/kg BW, equivalent to 4.0 mg Minimum lethal dose when 2 ' KCN/kg BW administered intravenously or intramuscularly Black vulture, Coragypa atrafus Single oral dose, as NaCN 1.6 mg CN/kg BW No deaths in 60 min. Mean 2 and maximum blood CN rnneentretions, in mg/kg FW, were 0.7 end 0.9, respectively 2.4 mg CN/kg BW Some deaths within 30 min. 2 Meen blood CN residues in ' mg/kg FW, were 0.7 in dead birds vs. 1.2 in those surviving 60 min 2.54 mg CN/kg BW Acute oral LD50; 95% C.I. of 2.3 2 and 2.8 mg CN/kg BW (4.4-5.3 mg NaCN/kg BWl 3.7 and 19.1 mg CN/kg BW All dead within 16 min; 2 maximum blood CN levels postmortem were 2.1 mg/kg FW in the low dose group and 4.2 in the high dose group ' Japanese quail, Coturnix japonica Single oral dose, as NaCN 4.5 mg CN/kg BW Acute oral LD50 for adult 2 ' females; 95% C.I. of 3.1 and 6.5 mg CN/kg BW 5.5 mg CN/kg BW Acute oral LD50 for adult 2 males; 95% C.I. of 4.0 and 7.5 mg CN/kg BW American kestrel, Falco sparuerius 2.12 mg CN/kg BW, as NaCN Acute oral LD50; 953. C.I. of 1.6 2 ' end 2.8 mg CN/kg BW Domestic chicken, Gallus domesticus ' Intravenous route 0.01 µg/kg BW Most of dose recovered in urine 8 as thiocyanate in 6 h; excretion limited by availability of transferable ' sulfur 0.6 mg CN/I:g BW, equivalent Lethal 2 to 1.5 mg KCN/kg BW 0.78 mg CN/kg BW, es KCN Sublethal; thiocyanate 4 excretion increased 10 times after 10 min and returned to normal levels after 3.5 h; the total thiocyanate collected was equivalent [o 85% of the administered dose t