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L~ <br /> <br />LJ <br />I' <br />I' <br />I~ <br />i~ <br />MSDS -Diesel <br />Sinclair Oil Corporation -August 2000 <br />HAZARDOUS DECOMPOSITION: <br />[ncomplete burning can produce carbon monoxide. <br />11. TOXICOLOGICAL INFORMATION <br />SYSTEMIC: <br />Petroleum-derived fuels and fuel oils aze complex and variable mixtures of hydrocarbons. <br />In general, the more viscous the mixttrre, the lcss toxic it will be. At high level exposures, <br />humans experience multiple organ failun:s, some of which may be due to hypoxia and <br />secondary to the failure of other organ systems. In humans kidney failure has been noted <br />only at high, acute levels ofexposutes, aid appears reversible. Liver emrymes may be <br />transiently elevated. At lower level cxposures, most acute health effects are revenrble. <br />People can be exposed by inhalation, ingestion and dermal contact. Frequently, people are <br />exposed by combined dermal and inhalation exposure. <br />ACUTE: <br />Inhalation: Headaches, confitsion, disorientation, b]tured vision occur with inhalation. <br />Higher exposures may cause hallucinations, CNS excitation, drowsiness, CNS depression. <br />Seizure and coma occur from very high exposures and death may result from respiratory <br />depression. ECG changes, cardiac arrhyrhmias, tachycardia, shock and cardiovascular <br />collapse can occur. Pneumonia, pulmon:uy edema aad hemorrhages can occur. <br />Inhalation of 8000-16060 mg/m3 for 2 tc 4 hours was lethal to tats. <br />' Ingestion: Central nervous system, cardiovascular, and trspiratory effects have been <br />reported with acute exposures to various hydrocarbon fuels and oils similar to those <br />reported with inhaiatioa Nausea, vomiting, cramping and diarrhea may occur. <br />' Eye: Conjunctivitis and burning, watery eyes have been reported in acute exposures to <br />various hydmcarbon fuels and oils. <br />' Skin: Mild erythema to full thickness ch_mical burns have occurred after prolonged <br />exposure to variotu hydrocarbon fuels and oils. <br />Chronic: <br />Chronic dermatitis with acanthosis, inflammation, parakeratosis and hyperkeratosis have <br />occurred with chronic exposures to various hydrocarbon fuels and oils. <br />Occupational exposures in petroleum refining are considered Group 2A (probably <br />carcinogenic) by IARC. <br />Page 5 of 7 <br />