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<br />National Irrigation Water Quality Program Guidelines <br /> <br />I <br /> <br />I <br /> <br />a particular compound to a particular <br />species without consulting the more <br />detailed information presented later in <br />each chapter and, when possible, the <br />original studies. <br /> <br />(4) Results from many recent studies could <br />not be included here. Most of the <br />research for these chapters was completed <br />by mid-1996, and only the literature pub- <br />lished prior to that time was system- <br />atically surveyed. During subsequent <br />review and preparation of this volume, <br />more recent results that came to our <br />attention were added opportunistically, <br />not systematically. <br /> <br />(5) Legally enforceable standards are not <br />presented here, with two exceptions. The <br />U.S. Environmental Protection Agency <br />has established "maximum contaminant <br />levels," applicable only to drinking water, <br />for most of these constituents, and the <br />U.s. Food and Drug Administration has <br />"action levels for human consumption" for <br />two of them (DOT and mercury). These <br />legal standards are noted near the end of <br />each chapter, in the section "Regulatory <br />standards." Note, however, that even in <br />those sections, values identified as "goals" <br />or "criteria" do not have the force of law. <br /> <br />Individual States may set legal standards that <br />are stricter than those of the Federal <br />Government, and many have chosen to do <br />so. State standards are too variable and <br />voluminous to be listed here; however, <br />Appendix I lists addresses and phone <br />numbers for the offices responsible for water <br />quality standards in each of the 17 Western <br />States. <br /> <br />The Need for Caution in <br />Interpreting Toxicological Data <br /> <br />The contents of this report are described as <br />guidelilles, rather than rules or standards, <br />because toxicological effects vary greatly in <br /> <br />CJ <br /> <br />natural ecosystems. Many variables can cause <br />individual constituents to be more or less toxic <br />at other sites or for other species. This section <br />describes some of the better known factors <br />that may complicate the interpretation of <br />toxicity data. <br /> <br />I <br /> <br />I <br /> <br />Unnatural Laboratory Settings <br /> <br />I <br /> <br />Most laboratory studies test toxicity under <br />completely unnatural conditions: they test the <br />effect of a single compound on a single <br />species, delivered by only one pathway under <br />carefully controlled conditions. In the wild, <br />organisms are exposed to many different <br />chemical and physical agents simultaneously. <br />(See "Interactions," below.) <br /> <br />I <br /> <br />I <br /> <br />I <br /> <br />Generally, laboratory specimens in an <br />experimentally contaminated environment are <br />given food from outside, uncontaminated <br />sources, whereas wild creatures must eat food <br />that has grown in the same environment and <br />that may have accumulated, through <br />bioconcentration, lethal levels of whatever <br />toxins are present. Thus, for instance, fish or <br />waterfowl could end up dying in areas where <br />waterborne toxin concentrations are at levels <br />that caused no harm to laboratory specimens. <br /> <br />I <br /> <br />I <br /> <br />I <br /> <br />On the other hand, most laboratory specimens <br />are taken from uncontaminated populations, <br />which have no previous history of exposure to <br />the toxin being tested. In the wild, organisms <br />living in a contaminated environment may <br />have acclimated or adapted to the toxin, <br />especially if the contamination developed <br />gradually. In this case, one might find fish <br />and waterfowl thriving in areas where <br />waterborne concentrations are at levels <br />experimentally determined to be lethal. <br /> <br />I <br /> <br />I <br /> <br />I <br /> <br />I <br /> <br />Laboratory specimens are rarely threatened by <br />predators or challenged by others of their own <br />kind in mating competitions, whereas their <br />undomesticated cousins deal with both <br />conflicts. These conflicts can add to the <br />overall stress on the organisms, making them <br /> <br />I <br /> <br />I <br /> <br />I <br /> <br />4 <br /> <br />I <br />