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Table 6. (continued) <br />Organism and arsenical <br />Effect <br />Referencea <br />Mule deer, Odocoileus hemionus <br />hemionus <br />Silvisar-510 (mixture of Single oral LD-50 dose >320 <br />cacodylic acid and tri- mg/kg BW; appetite loss. <br />ethanolamine cacodylate) <br />White-tailed deer, Odocoileus <br />virginianus <br />Sodium arsenite (used to <br />debark trees) <br />Arsenic acid (herbicide to <br />control Johnson grass) <br />Lethal dose of 923 to 2,770 <br />mg equivalent to about 34 mg/kg <br />BW; liver residues of 40 mg/kg <br />fresh weight. <br />23 deer killed from apparent <br />misuse. Arsenic levels, in <br />mg/kg fresh weight, in deer <br />found dead were 19 in liver, <br />18 in kidney, and 22.5 in <br />rumen contents. Soils from <br />area contained - 2.4 mg As/kg, <br />and water 0.42 mg As/1. <br />Domestic sheep, Ovis aries <br />Arsanilic acid <br />Sodium arsenite <br />One-year-old castrates fed <br />diets with 273 mg As/kg <br />for 28 days had 0.54 mg As/l <br />in blood, 29 mg/kg dry <br />weight in liver, 24 in <br />kidney, and 1.2 in muscle <br />(vs. <0.01 in all control <br />tissues). After 6 days on <br />an As-free diet, liver re- <br />sidues were <5 mg/kg DW. <br />Maximum tissue levels in <br />sheep fed diets containing <br />27 mg As/kg for 28 days <br />were 3.2 mg/kg DW kidney; <br />for an 144 mg/kg diet, <br />the maximum tissue level <br />was 27 mg/kg DW liver. <br />Single oral dose of 5 to <br />12 mg/kg BW (0.2 to 0.5 <br />grams) was acutely toxic. <br />17 <br />12 <br />12 <br />7 <br />3 <br />68