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2009-05-19_REVISION - M1977416 (29)
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2009-05-19_REVISION - M1977416 (29)
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Last modified
6/15/2021 2:18:35 PM
Creation date
5/27/2009 2:19:22 PM
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Template:
DRMS Permit Index
Permit No
M1977416
IBM Index Class Name
REVISION
Doc Date
5/19/2009
Doc Name
EPP(AM-01) Att 4: Bioavailability; Att 5: Water Bal; Att 6: Percolation; Att 7: Lab Rpts. (part 4)
From
Denison Mines
To
DRMS
Type & Sequence
AM1
Email Name
RCO
Media Type
D
Archive
No
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• AT = Carcinogenic Averaging Time (period over which exposure resulting <br /> incarcinogenic effects is averaged - years) <br />EF = Exposure Frequency (days/year) <br />SF. = Oral Carcinogenic Potency Slope (mg/kg-day)- 1 <br />CF = Conversion Factor (kg/mg) <br />Nco = Number of COCs with an Oral Carcinogenic Potency Slope (unitless) <br />MN = Number of Media <br />IRS = Age Adjusted Soil Ingestion Rate (mg-yr/kg-day) <br />SF, = Inhalation Carcinogenic Potency Slope (mg/kg-day)-1 <br />Nci = Number of COCs with an Inhalation Carcinogenic Potency Slope (unitless) <br />IR = Inhalation Rate (m3/hr) <br />• <br />Default Exposure Parameters: <br />BLM default values for several of the input parameters identified below were provided by Karl <br />L. Ford, Ph.D. (BLM National Science and Technology Center) in a January 6, 2009 telephone <br />conversation and email correspondence (CDM 2009). <br />* 30 years for adult exposure and 6 years for child exposure. <br />As discussed above, the camper scenario is the most conservative BLM exposure scenario that is <br />also appropriate for current and future site conditions. <br />Key RMC Input BLM Receptors <br />Parameter Camper ATV Driver Worker Surveyor <br />EF (days/year) 14 5 40 5 <br />ED ears 30/6* 30 30 30 <br />IR (mg/ da 114 114 114 114 <br />IHR m3/hour 1.28 3.9 2.5 2.5 <br />ET hr/ day) 24 4 8 8 <br />Mn 5 1 1 1 <br />Relative Bioavailability(RBA): <br />As discussed above, site-specific bioavailability can be a key factor in developing appropriate <br />RMC for the Site. Relative bioavailability (RBA) is measured using an in vitro test, referred to as <br />the Relative Bioavailability Leaching Procedure (RBLP) or in vitro bioaccessibility assay (IVBA). <br />This test has been developed by EPA Region 8 and the University of Colorado. The IVBA test <br />measures the fraction of lead or arsenic solubilized from a soil sample under simulated <br />gastrointestinal conditions. For the Site, only the arsenic results will be pertinent. The in vitro <br />test uses a warm (38C) weak acid solution, into which the contaminant is introduced. After a <br />prescribed time period, the solution is analyzed for arsenic. The mass of arsenic found in the <br />filtered extract is compared to the mass introduced into the test. The fraction liberated into the <br />aqueous phase is defined as the bioaccessable fraction of arsenic in that media or the relative <br />bioavailability (RBA); typical RBA values for arsenic in soil are between 0.5 and 0.8. Additional <br />information regarding the IVBA test method is available at the following website: <br />http: / / www.colorado.edu / geolsci/ legs/ invitrol.html. <br />0
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