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HAZARDS IDENTIFICATION(continued) <br />Central nervous system stimulation followed by central <br />• nervous system depression may occur with hypoxic convulsions <br />and death due to respiratory arrest. <br />Higher exposures may lead to rapid respiration and pulse, <br />flushing, cyanosis, acidosis, thyroid effects sometimes <br />observed in individuals with nutritional deficiencies, <br />symptoms associated with Parkinsonian Syndrome, pulmonary <br />edema, and fatality from gross overexposure. In the few <br />-cases of disturbance of vision or damage to the optic nerve <br />or retina attributable to cyanide poisoning, the poisoning <br />has been acute and severe, and lethal or near lethal. There <br />are reports of increased incidence of insomnia, agitated <br />sleep, tremors, dermatitis and nose bleed in electroplating <br />workers. <br />Individuals with preexisting diseases of the central nervous <br />system may have increased susceptibility to the toxicity of <br />excessive exposures. <br />Carcinogenicity Information <br />None of the components present in this material at concentrations <br />equal to or greater than 0.1% are listed by IARC, NTP, OSHA or ACGIH <br />as a carcinogen. <br />FIRST AID MEASURES <br />• Compound-Specific First Aid ~ Notes to Physicians <br />A step-wise procedure of "First Aid" and "Medical Treatment" is <br />recommended for any cyanide poisoning. Treatment requires <br />immediate action to prevent harm or death. First Aid is given <br />initially, and experience shows that when given promptly it is <br />usually the only treatment needed for typical accidental <br />poisonings. Medical treatment may be needed for more severe <br />poisoning. <br />First aid treatment uses oxygen and-amyl nitrite and can be given <br />by a f first responder before medical help arrives. <br />Medical treatment is given if the patient does not respond to <br />First Aid. Medical Treatment is a more aggressive treatment <br />requiring intravenous injections of sodium nitrite and sodium <br />thosulfate, and must be administered by qualif ied medical <br />personnel. It provides a larger quantity of antidote which helps <br />eliminate cyanide from the body. Even if a doctor or nurse is <br />present, the need for fast treatment dictates using the First Aid <br />procedure with oxygen and amyl nitrite while Medical Treatment <br />materials for intravenous injection are being prepared. When <br />antidotal treatment is necessary, it should be started immediately. <br />IN CASE OF CYANIDE POISONING, START FIRST AID TREATMENT <br />IMMEDIATELY, THEN CALL A PHYSICIAN. <br />(Continued) <br /> <br />1252CR Page 3 <br />