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10. STABILITY and REACTIVITY (Continued) <br />MATERIALS WITH WHICH SUBSTANCE IS INCOMPATIBLE: Carbon Dioxide will ignte and explode when heated with <br />powdered aluminum, beryllium, cerium alloys, chromium, magnesium-aluminum alloys, manganese, thorium, titanium, and <br />zirconium. In the presence of moisture, Carbon Dioxide will ignite with cesium oxide. Metal aptylides will also ignite and <br />explode on tooted with Carbon Dioxide. <br />HAZARDOUS POLYMERIZATION: Will not occur, however Carbon Dioxide ads to catalyze the polymerization of <br />acrylaldehyde and aziridine. <br />CONDITIONS TO AVOID: Avoid exposing cylinders of Carbon Dioxide to extremely high temperatures, which could cause <br />the cylinders to rupture or burst. Do not store the solid form d Carbon Dioxide in gas-tight containers, which could also <br />cause over-pressurization and rupture of the container. <br />PART IV is there any otheruseful information about this material? <br />11. TOXICOLOGICAL INFORMATION <br />TOXICITY DATA: Carbon Dioxide is an asphyxiant gas, which has physiological etfeds at high conpntretions. The <br />following toxicdogipl data are available for Carbon Dioxide. <br />CARBON DIOxIDE: CARBON DI01(IDE (wndnued): CARBON DIOXIDE (eontinued): <br />LCLO (Inhalation-Human) 9 ppNS minutes TCLO (Inheletlon-RebbR) 27,000 pprtJ24 TCLo (Innalaton-Mouse) 2 ppNB Murs: <br />LCIO (Inhalation-Mammal-spades hours130 dayscontinuous Behavioral: tamale 10 day(s) after conception: <br />unspedfied) 90000 ppml5 minutes somndence (general depressed acfivity) Reprodudhre: Fertility: post-hnplanbtion <br />TCLO (Inhalator-Ftat) 10W0 pprtJ24 TCLo (Inhalatbn-Rebdt) 13 ppN4 haws: mortality (e.g. dead andlor resgbed <br />txxrrsrdayscontinuous: &ood: other female 412 day(s) after wnception: impbms par tidal number of implants); <br />changes Fieprodudive: Spedfic Devebpmantel SpeaAc DevebpmenW Abrgrtnalities: <br />TCLo (InhalatiarRat) 6 pptJ24 hours: tamale Abnormalities: muswbskelelal system mus~ubskeletal system <br />10 day(s) after conception: Reproductive: TCLn (Inhaaton-Mouse) 55 ppN2 hours: <br />Spedric Devebpmental Abnomtelifbs: male 3 day(s) pre-metlng: ReprodudNe: <br />muscubskebtal system. cardiwasrvbr Paternal Eflecls: spemlalogerresis (ind. <br />(dreulatay) systerrr, respiratory system genetic matedel, sperm morphobgy. <br />TCLO (bhalatbrfRet) 6 pphl24 hours: female motility, and count) <br />10 day(s) after cocepton: Reproductive: TCLo (Inhaaton-Mouse) 55 ppN4 tqurs: <br />Efleds on tJewbom: groMh statistics male 6 day(s) pre+nafing: Reproductive: <br />(e.g.%, reduced weight gain) Fertilfty: mab fer#tiry index (e.g. # males <br />Impregnating /emabs per # males exposed <br />b ledse nonpregnenl females) <br />SUSPECTED CANCER AGENT: Carbon Dioxide is not found on Ute following lists: FEDERAL OSHA Z LIST, NTP, <br />CAUOSHA, IARC, and therefore is not considered to be, nor suspeded to be a pnprcausing agent by these agencies. <br />IRRITANCY OF PRODUCT: Goofed with repidty expanding gases pn puss frostbite and damage to exposed skin and <br />eyes. Due to the formation d prbonic acid, this gas mixture pn be slightly irritating to contaminated eyes. <br />SENSITIZATION OF PRODUCT: Carbon Dioxide is not a sensitizer attar prolonged or repeated exposures. <br />REPRODUCTNE TOXICITY INFORMATION: Listed bebw is information concerning the efleds of Carbon Dioxide on the <br />human repradudive system. <br />Mutacenicily: Carbon Dioxide is not expected to puss mtrtagenic etfeds in humans. <br />EmbrvotoxciN: Carbon Dioxide has not been reported to puce embryotoxic eifeds; sea next paragraph for information. <br />Teretocenicity: Carbon Dioxide is not expelled to puss teretogenic effects in humans. Clinical studies involving test <br />animals exposed to high conpntrations of Carbon Dioxide indicate teretogenic efleds (e.g., pfdiaC and skeletal <br />malformations, stillbirths). <br />Reorodudive ToxidN: Carbon Dioxide is not expelled to pose adverse reproductive efleds in humans. Studies involving <br />test animals exposed to high conpntrations of Carbon Dioxide indipte reproductive efleds (e.g. changes in testes). <br />A mutaaen is a chemipl which causes permanent changes to genetic material (DNA) such that the changes will propagate <br />through gene2tion lines. An embrrotoxin is a chemical which poses damage fo a developing embryo (i.e. within the first <br />eight weeks of pregnancy in humans), but the damage does not propagate across generational lines. A teratoaen is a <br />chemipl which causes damage to a devebping fetus, but the damage does not propagate across generational lines. A <br />reorodudive toxin is any substance which infeAeres in anyway with the reproductive process. <br />MEDICAL CONDITIONS AGGRAVATED BY EXPOSURE: Disorders involving the "Target Organs" (see Section 3, Hazani <br />Information) may be aggravated by Carbon D'loxide overexposure. <br />RECOMMENDATIONS TO PHYSICIANS: Treat symptoms and redup overexposure. <br />BIOLOGICAL EXPOSURE INDICES (BElsl: Curtently, Biologipl Exposure Indies (BEIs) are not applipble for Carbon <br />Dioxide. <br />CARBON DIOXIDE - CO= MSDS (DOCUMENT#001ot3) PAGE 8 OF 12 <br />