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Product Safety Assessment: DOWTm Methyl Isobutyl Carbinol <br />preferred. Use of a direct water stream may spread the fire. The public should be warned of <br />any downwind vapor explosion hazards. Vapors are heavier than air and may travel a long <br />distance and accumulate in low -lying areas. Keep vapors out of sewers. Firefighters should <br />wear positive - pressure, self- contained breathing apparatus (SCBA) with an approved full -face <br />mask and protective firefighting clothing. See Physical Hazard Information. <br />For more information, see the relevant Safety Data Sheet. <br />Back to top <br />Health Information 14,15 <br />Eye and Skin Contact— May cause moderate eye irritation or moderate corneal injury. Exposure <br />to methyl isobutyl carbinol vapor may cause eye irritation, mild discomfort, and redness. <br />Prolonged skin contact may cause slight irritation and local redness or drying and flaking of the <br />skin, but is unlikely to result in absorption of harmful amounts. <br />Inhalation — Prolonged, excessive exposure to methyl isobutyl carbinol may cause adverse <br />effects. Excessive exposure may cause irritation to the upper respiratory tract and lungs. <br />Symptoms of excessive vapor exposure may be anesthetic or narcotic effects, dizziness, and <br />drowsiness. <br />Ingestion — Methyl isobutyl carbinol has low toxicity if swallowed. Small amounts swallowed <br />incidental to normal handling operations are not likely to cause injury; however, swallowing larger <br />amounts may cause injury. <br />Excessive exposure— Excessive exposure may cause anesthetic or narcotic effects, dizziness, <br />and drowsiness. Kidney toxicity has been reported in animal studies. <br />Other— Methyl isobutyl carbinol is unlikely to be mutagenic in humans. Based on the available <br />data from animal studies, this material is not expected to be a human reproductive or <br />developmental toxicant. <br />For more information, see the relevant Safety Data Sheet <br />Back to top <br />Environmental Information 16,17 <br />DOWTM methyl isobutyl carbinol is moderately volatile and moderately soluble in water. As a <br />result when introduced to water, the chemical will have a tendency to remain in water. It has low <br />potential to bind to soil or sediment. <br />DOW methyl isobutyl carbinol is unlikely to persist in the environment. The compound is readily <br />biodegradable, which suggests the chemical will be rapidly and completely removed from water <br />and soil environments, including biological wastewater treatment plants. <br />DOW methyl isobutyl carbinol is not likely to accumulate in the food chain (bioconcentration <br />potential is low) and is practically nontoxic to fish and other aquatic organisms on an acute basis <br />The Organisation for Economic Co- operation and Development (OECD) Screening Information <br />Data Set (SIDS) Initial Assessment Profile for methyl isobutyl carbinol concluded that the <br />a" Trademark of The Dow Chemical Company ( "Dow ") or an affiliated company of Dow <br />Created: June 26, 2009 The Dow Chemical Company Page 3 of 6 <br />