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<br />'ll.e brain cavities awl sJ;lual cO.ru nave formed by contraction <br />of the neural plate. ine eye rudlffi~lts h~ve formed and are seen as <br />I <br />lat~ral fJI'otrusio!ls a.t the C:i.l~';,0riGr ellG. o~' tnt; ol'ail!. 'I'he prosen- <br />cephalon (fore0rai~), mesencephalon (midbraiu) ~ld rhombeficaphalon <br />lhia~~rain) are easily distll~uisheJ. T~e auditory vessicles arc <br />forillll~ at the level uf the hindbrain. 1he first pair of somites <br />have formed. <br />Stage 18: Cavities in the Eye Rudiments: 53 hr. <br />'The optic placodes (eye rUG iments) have elongated and contain <br />narrow vessicles. ihe head fold is now visible: subcephalic pocket <br />and ant-erior intes'cinal portal are ventrad. to heau. 'lhe auditory <br />placodes are formed. There are now 14 to 16 pairs of samites. <br />St.age 19.: Ovalt.;,y8s: Yl hI'; 2.5 laIn. U'ig. 2g). <br />- ~hc optic.placodes are rounded to oval. Vessicles are not yet <br />pI'esen~ in the ~uditQry placodes. There are thirty pairs of somites. <br />'ih<:: t.ail process is quite dist.inguished. <br />stage 20: Early'l'ailbud: 65 hI'; 3.0 Iillil. (Fig. Ja). <br />The optic vessicles are somewhat flattened on their outer mar- <br />gins: The leas i3 nu~ forming. 1~e audi~ory ~lacodes have develop- <br /> <br />8-.'~ .:..:.. ~11.~11 <br /> <br />,-. ," : -.: , <br />_:..-.,. 'J ..i. ...,.; . <br /> <br />.:i. :::::::..:...:'1 l.al._t.-u.l ~;:c-:.:; G.0velopej and protrudes from <br /> <br />tfle yolk. sphere. '1:1e foregut is forming. <br />Stage 21: Late 'l'ailbud.: da.y 4; 78 hI'; J.8 mm. (F'ig. 3b). <br />'1'he embryo is subdivided into two parts: anterior portion con- <br />sisting of head and anterior tru.llk overlying spherical yolk mass; <br />posterior portion consisting of posterior trunk and tail overlying <br />cylind.ri cal ~'olk mass. 'Eba opt i c st8.1 k s and cups can be di stingui sh- <br />ed as well as the lens. 'rhe prose~"lc;.Jp;l-::llon is .colOW divisible into <br />telencephalon (future cerebrum) and diencephalon (future epithalamus, <br />t.nalalilus and hypothala::a.us); the rhombeflcephalon is now divisible in- <br />(,0 Ii1e l.encephalon. (fu "LUl'!.:: cere bellum) . and illyeleLlcephalon (future med-.. <br />ulla oblongata). ..I.he heart rudiment 1.:3 preseLlt. 'Ihe tailbud is ' <br /> <br />1 eL16 t hellinE,. <br /> <br />'l'he enbl''yo is motile witilill the egg chori.oLi. <br /> <br />SLube 22: Heart. Beat: c.J h1'; 1':'.0 lili!l. <br /> <br />" <br /> <br />-~;-, ,....~ -~- ~:'I'_:':" ' <br /> <br />, ~'" ~~.\,,----:-,-,...; -9":"'''-, <br /> <br />.a_........_.....~ ..._.._..,....- ....._.....~...__ . ..,..,-_ <br />