<br />AChE inhibition in Colorado squawfish
<br />
<br />939
<br />
<br />...
<br />
<br />environmental factors like food availability, temperature,
<br />and biological interactions. The emergence of mathematical
<br />modeling in aquatic toxicology and in related disciplines pro-
<br />vides new opportunities for extrapolating within-organism
<br />responses to ecologically relevant end points [34,35]. By in-
<br />tegrating bioenergetic considerations, toxicological concen-
<br />tration-response relations, and environmental influences,
<br />mathematical models may unravel complex interactions and
<br />provide reliable predictions of toxicant effects based on
<br />within-organism end points.
<br />
<br />.
<br />
<br />Acknowledgement- We thank John D. Tessari and Thomas J. Keefe
<br />for technical advice and assistance. Heidi T. Bestgen, William H. Cle-
<br />ments, Michael S. Farmer, Peter M. Kiffney, and two anonymous
<br />reviewers provided comments that improved the manuscript. This
<br />study was supported by a cooperative agreement with the Grasshop-
<br />per Integrated Pest Management Project of the U.S. Department of
<br />Agriculture-Animal and Plant Health Inspection Service, Lowell C.
<br />McEwen, principal investigator.
<br />
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