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Laughlin et al. 1986a). Tributyltin is a contributory factor and probably a <br />major cause for the reproductive failure of the European flat oyster (Ostrea <br />eduiis) in recent years in some locations (Thain and Waldock 1986). In fact, <br />tributyltins are capable of causing adverse biological effects at levels far <br />below that of any previously reported marine pollutant (Lawler and Aldrich <br />1987). <br />The widespread agricultural applications of trialkyltin biocidal agents <br />have greatly increased the relative exposure risks to workers handling these <br />materials (Rosenberg et al. 1985). Internationally, tin was recognized as a <br />potential environmental contaminant at the Paris and Helsinki conventions in <br />1974; in later conventions, organotin compounds were moved to the "black list" <br />(Vrijhof 1985). Due to the increasing use of organotin compounds as a class, <br />the Canadian government, in 1979, placed organotins on Canada's Category III <br />Contaminant List. Category III indicates that additional data are needed on <br />the occurrence, persistence, and toxicity of organotins for preparation of <br />informed environmental and human health risk assessments (Chau et al. 1984). <br />Many reviews and bibliographies are available on the environmental <br />impacts of inorganic and organic tin compounds. These authorities agree that <br />inorganic tin compounds are comparatively harmless and that many organotin <br />compounds are potentially very hazardous to natural resources--especially <br />tributyltin compounds to aquatic biota. One rare exception to this <br />generalization involved 113 cases of acute gastrointestinal illness in <br />Washington and Oregon in 1969 associated with ingestion of canned tomato juice <br />contaminated by inorganic tin; detinning in many cans resulted in tin levels <br />as high as 477 mg inorganic tin per liter of juice. It seems that excessive <br />use of nitrate fertilizer on one tomato crop was the ultimate cause of the <br />detinning (Barker and Runte 1972). <br />This report summarizes selected data on ecological and toxicological <br />aspects of organic and inorganic tin compounds, with emphasis on fishery and <br />wildlife resources. It is part of a continuing series of reports on chemical <br />contaminants prepared in response to informational requests from environmental <br />specialists of the U.S. Fish and Wildlife Service. <br />IBarnes and Stoner (1959); Piver (1973); Kimbrough (1976); CEC (1978); <br />Zuckerman et al. (1978); Duncan (1980); Watanabe (1980); WHO (1980); Blunden <br />and Chapman (1982); Blunden et al. (1984, 1985); Krigman and Silverman (1984); <br />Reiter and Ruppert (1984); Reuhl and Cranmer (1984); Wilkinson (1984); Hall <br />and Pinkney (1985); Laughlin and Linden (1985); McMillan and Wenger (1985); <br />Thompson et al. (1985); Blunden and Chapman (1986); Cardwell and Sheldon <br />(1986); Chang (1986); Maton (1986); Sylph (1986a, b); EPA (1987); Snoeij et <br />al. (1987). <br />2